|
 
 
 

Postdoctoral Position in immunopeptidomics

A post doctoral position is available at the Immunopeptidomics Unit headed by Dr. Michal Bassani-Sternberg at the Oncology Department of the University Hospital of Lausanne (CHUV/UNIL). The Immunopeptidomics Unit is incorporated into the hiTIDE (human integrated tumor immunology discovery engine) translational research group led by Prof. George Coukos. In addition, the unit is affiliated to the Center of Experimental Therapeutics (CHUV) and to the Ludwig Institute for Cancer Research.

Département
Dpt d'oncologie (DO)
Code emploi
1er Assist.Uni 3e An - 1108
Niveau
Hors DECFO
Date d'entrée souhaitée
01-07-2018
Type de contrat
CDD
Catégorie professionnelle
Médico-techniques
Lieu
Lausanne
Taux d'activité
100%
Date de début de publication
04-05-2018
Date de fin de postulation
15-06-2018
Référence
02829-MT-209-2018
Documents

Contexte

In collaboration with the Vital-IT group at the Swiss Institute of Bioinformatics (SIB), we established a continuous proteo-genomics bioinformatic pipeline enabling direct identification of neoantigens by combining genomic information derived from exome-seq analysis with measured immunopeptidomics mass spectrometry data. Our main goal is to identify clinically relevant and novel cancer-specific human leukocyte antigen (HLA) ligands that will guide the development of personalized cancer immunotherapy. We are involved in first-in-man phase I clinical trials where we are responsible for identifying neoantigens individually from tumor samples, which are further used to identify tumor neoantigen-specific T cells for adoptive T cell therapies. In addition, we pursue fundamental discovery work to elucidate how tumour cells present antigens, and what are the molecular bases of tumour immunogenicity.

We are seeking to hire a post doctoral fellow with solid expertise in genomics, transcriptomics and/or proteomics data analysis to join our team and to utilize this pipeline to further explore the antigenic landscape of tumors. 

Mission

  • Development and application of proteo-genomics pipelines for personalized antigen discovery
  • Application of mass spectrometry based immunopeptidomics in basic research and clinical vaccine trials.

Profil

  • PhD in biology, medicine, bioinformatics, computer science or mathematical statistics
  • The position requires outstanding quantitative and analytical skills
  • Expertise in large-scale data analysis of NGS and MS proteomics is a plus
  • Expertise in systems biology/systems medicine, integration and visualization is a plus
  • Knowledge in immunology and cancer research
  • The position requires the ability to work in interdisciplinary projects, strong teamwork and communication skills, reliability, attention to detail and effective time management
  • Fluent in English language.

Nous offrons

  • Becoming an employee of the University Hospital Center from the canton of Vaud is the assurance of:
  • First-rate social benefits
  • Regular salary progression adapted to the responsibilities
  • A right to three days of minimum training per year
  • 25 days vacation per year
  • Hotel-quality corporate restaurants in each of the institution's buildings.

Contact et envoi de candidature

For more information, please direct your questions to Prof. Michal Bassani at Michal.Bassani@chuv.ch

The application should include:

-Application letter

-Curriculum vitae, qualifications and description of previous research/work

-Publication list (with three most relevant publications marked)

 

Only applications through this website will be taken into account.

Soumettre ma candidature

Postuler