A post doctoral position is available at the Immunopeptidomics Unit headed by Dr. Michal Bassani-Sternberg at the Oncology Department of the University Hospital of Lausanne (CHUV/UNIL). The Immunopeptidomics Unit is incorporated into the hiTIDE (human integrated tumor immunology discovery engine) translational research group led by Prof. George Coukos. In addition, the unit is affiliated to the Center of Experimental Therapeutics (CHUV) and to the Ludwig Institute for Cancer Research.
In collaboration with the Vital-IT group at the Swiss Institute of Bioinformatics (SIB), we established a continuous proteo-genomics bioinformatic pipeline enabling direct identification of neoantigens by combining genomic information derived from exome-seq analysis with measured immunopeptidomics mass spectrometry data. Our main goal is to identify clinically relevant and novel cancer-specific human leukocyte antigen (HLA) ligands that will guide the development of personalized cancer immunotherapy. We are involved in first-in-man phase I clinical trials where we are responsible for identifying neoantigens individually from tumor samples, which are further used to identify tumor neoantigen-specific T cells for adoptive T cell therapies. In addition, we pursue fundamental discovery work to elucidate how tumour cells present antigens, and what are the molecular bases of tumour immunogenicity.
We are seeking to hire a post doctoral fellow with solid expertise in genomics, transcriptomics and/or proteomics data analysis to join our team and to utilize this pipeline to further explore the antigenic landscape of tumors.
For more information, please direct your questions to Prof. Michal Bassani at Michal.Bassani@chuv.ch
The application should include:
-Curriculum vitae, qualifications and description of previous research/work
-Publication list (with three most relevant publications marked)
Only applications through this website will be taken into account.